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For competitive athletes, IGF-1 and its analogs, including LR3, are banned at all times, in and out of competition, under Section S2 of WADA's Prohibited List (Peptide Hormones, Growth Factors, Related Substances and Mimetics)
Dosage protocols used in preclinical research vary depending on the study design and research objectives
Increased NNMT expression has also been reported in muscle-wasting conditions such as Duchenne Muscular Dystrophy (DMD)
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