The FDA includes a warning about medullary thyroid carcinoma and advises against use in individuals with a family history of the disease or a family history of MEN 2
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Pregnancy planning also affects durationmedication-specific washout periods apply (approximately 2 months for semaglutide, 1 month for tirzepatide/dulaglutide, and immediate discontinuation for liraglutide when pregnancy is recognized)
Acta Biochim Biophys Sin 53:11891197
Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, et al