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Inhibition of protein arginine methyltransferase 5 suppresses GPX4 methylation, reduces GPX4 levels, and increases sensitivity to ferroptosis inducers [42]

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PMID 24442756

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It has been shown that microglia exposed to LPS displayed a primed phenotype with heightened levels of inflammatory markers such as iNOS, IL-1, and p65, which were accompanied by iron deposits and ferroptosis (41)