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It is FDA approved for venous ulcers of greater than one month duration that have not adequately responded to standard therapy, as well as diabetic foot ulcers of greater than one-month duration (Nicholas 2016
This comparison examines how these two interventions differ in mechanism, evidence quality, practical accessibility, and potential complementarity
Well-designed clinical trials in humans are needed
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Despite widespread anecdotal reports of effectiveness, robust clinical data in humans is lacking, with most research being conducted in animal models 6 7
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