While it is unknown whether liraglutide causes the same risk in humans, the drug is contraindicated in people with MEN2 or a personal or family history of MTC
This selectivity has been attributed to its specific binding characteristics at the GHSR-1a receptor
Research shows some concern about several ARVs, but only efavirenz proved to have a significant impact on hormonal birth control
(9) A Nakamura, T Sugao, K Yamaue, M Kobatake, et al (1989) Involvement of spinal noradrenergic system in the mechanism of an antinociceptive effect of delta-sleep-inducing peptide (DSIP) Brain Research, 1989 Feb 20, Volume 480 (Issues 1-2), Pages 82-6
Peptide aggregation is irreversible and indicates that the peptide has lost its native structure, rendering it inactive