Patients over 65 years require particular attention to muscle preservation, as excessive lean mass loss can impair functional independence and increase fall risk
Direct the stream against the vial wall, not directly onto the powder cake
The article also flags patients with limited dexterity, vision impairment, or no access to sterile supplies, who may be better served by pre-filled injection pens or provider-administered doses
The clinical relevance of these results seems also highlighted by the evidence that for some outcomes the clinical benefit is consistent irrespective of the presence of type 2 diabetes [13], advanced age [13, 30], and the background cardiorenal disease [12, 15, 31]
Longer-term study will still be needed and is planned. From the Editor of JCEM Case Reports JCEM Case Reports William F