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Consumption of unprocessed red meat, total meat (unprocessed and processed), or foods of animal origin was associated with higher risks of ASCVD by 15%, 22%, and 18%, respectively, when comparing participants who consumed more meat products (last quintile) with those who consumed the least (first quintile)

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However, as genotyping is not currently routinely available and serum vitamin B 12 measurement is cheap, our results reinforce the causal association of metformin treatment with vitamin B 12 deficiency and guideline recommendations for routine screening for vitamin B 12 deficiency in people treated with metformin

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