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[4] Elevated NAD+ acts as a co-substrate for sirtuins, specifically activating SIRT1 often called the longevity gene. SIRT1 activation drives increased mitochondrial biogenesis and metabolic rate

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References to clinical trials and published research throughout this description are provided for informational and research context only and do not constitute medical claims or endorsements of any therapeutic application of this product.

The compounds quinolinium scaffold mimics nicotinamides structure, allowing it to compete for the NNMT active site while avoiding interactions with other enzymes

The provider needs to evaluate a condition beyond simply deciding to give the shot