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This activation has been shown to upregulate genes involved in collagen synthesis, cell proliferation, and differentiation while potentially downregulating matrix metalloproteinases

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INTRODUCTION Vitamin B12 is essential for DNA synthesis, red blood cell formation, and neurologic function[] and is also involved in the metabolism of fat and carbohydrate.[] The clinical manifestations of vitamin B12 deficiency are the effects of depletion on multiple systems, and their severity varies greatly

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