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Wiser et al., 2010
This catches any developing issues early
Higher volume clinics sometimes use 20 mg/mL or even 40 mg/mL to minimize injection volume and maximize doses per vial
Tirzepatide works through several mechanisms: it slows gastric emptying, enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, and acts on central appetite-regulating pathways in the brain
Typically, for weight loss, providers start with a low dose (e.g., 0.25 mg once weekly) to lessen side effects, gradually increasing to a higher doseoften up to 2.4 mg weekly in the case of Wegovy
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