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While occasional nausea is common, frequent vomiting that prevents adequate fluid or food intake warrants prompt evaluation by a healthcare provider

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Inform patients using these concomitant medications of the risk of hypoglycemia and educate them on the signs and symptoms of hypoglycemia Acute Kidney Injury Due to Volume Depletion: There have been postmarketing reports of acute kidney injury in some cases requiring hemodialysis, in patients treated with semaglutide

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The commonly referenced therapeutic range of 0.25-0.5 mg daily (250-500 mcg) extrapolates from the effective rat dose of approximately 10 mcg/kg body weight

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Colbourne JRM, Fisher OM, Mo S, et al

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