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2 T2DM causes changes in cognitive function 2.1 Cognitive impairment in T2DM: stages and risk factors In individuals with T2DM, cognitive functioning undergoes distinct stages of impairment, ranging from diabetes-associated cognitive decrements to MCI and dementia ( The intricate relationship between hyperglycemia, hyperinsulinemia, and the brain reveals substantial connections to cognitive decline ( 2.2 Dopamine and cognitive function in diabetes Dopamine (DA), a neurotransmitter known for its role in regulating behavior and movement, also modulates cognitive function
