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Study findings BDNF-TrkB signaling plays a critical role in regulating cellular metabolism pathways, including glutathione-ascorbate and energy metabolism

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BPC-157 operates primarily at the local tissue level: it upregulates VEGF and EGF expression at the injury site, modulates the nitric oxide system to improve blood flow to damaged tissue, and directly promotes fibroblast migration and collagen organization through the FAK-paxillin pathway

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