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Individual evidence for inositol : Systematic reviews and meta-analyses have shown that myo-inositol supplementation may modestly improve metabolic parameters in women with PCOS, including reductions in fasting insulin, improvements in insulin sensitivity, and small decreases in body mass index (BMI)

(2018) used the current understanding from tendon, ligament and bone and applied this to gastrointestinal tract healing, which could provide a pathway for understanding of the systemic healing capabilities for applications to other tissues

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What I found in reviewing the data is that most gastrointestinal side effects peaked during dose escalation and reduced once participants reached their maintenance dose