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The schedule mirrors the clinical-trial protocols that drove significant weight loss around 15% of body weight over 68 weeks on 2.4 mg weekly [2] while holding gastrointestinal effects down through gradual escalation [1] [4]
The GLP-1R agonist liraglutide increases myocardial glucose oxidation rates via indirect mechanisms and mitigates experimental diabetic cardiomyopathy
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