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This dual activation produces a documented synergy, with a GH area under the curve (AUC) 2 to 4 times greater than each peptide administered alone
Using a nasal spray eliminates the need for reconstitution, and dosing is straightforward with the metered spray format
The peptide also decreases cyclooxygenase-2 (COX-2) gene expression
Why are GLP-1 agonists contraindicated in specific populations, such as pregnant individuals or those with severe gastrointestinal disorders, and what alternative treatment approaches could providers consider in these cases
Shilpa Paradkar Singh, MD | Last reviewed June 2026 Access to the latest FDA-approved medications tailored to your biology
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