Short-term treatment with liraglutide positively impacts the microbiome, while prolonged dulaglutide treatment leads to gradual changes in the microbial community, mirroring the slow and steady progress in glycemic control, weight loss, and reduction of inflammation [99,100]
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Results from the BELIEVE trial showed that after 72 weeks, participants receiving the combination therapy experienced an average weight reduction of 22.1% , significantly outperforming Bimagrumab alone (10.8%) and semaglutide alone (15.7%)