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This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice
However, the longevity of results can vary depending on factors such as age, lifestyle, and the specific treatment used
BPC-157 blocks amphetamine stereotypy and rescues haloperidol-induced catalepsy BPC-157 is anti-nociceptive in an incisional-pain model but if you need it in a pinch it counteracts morphines analgesia and lithium toxicity BPC-157 corrects basically any electrolyte problem in any direction: hyperkalemia, hypermagnesemia, and honestly you should just read this litany of various electrolyte disturbances that BPC-157 handles with ease BPC-157 reverses both atropine mydriasis and drug-induced miosis in the same rats and guinea pigs
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