Up-and-coming medications such as Retatrutide and Cagrilintide are on the horizon, indicating a potential shift in treating obesity and managing diabetes
As research progresses, personalized medicine approaches, novel drug formulations, and combination therapies will shape the future of obesity pharmacotherapy
As a consequence, the peptide might lead to fat accumulation rather than reduction, as its substantial hunger-inducing impact could offset the fat-burning benefits of increased GH levels
This effect was inhibited by endothelium removal or NOS blockade, indicating that NO plays a crucial role in the vasodilatory response
10.2337/db16-1009 Summary Keywords GLP-1 receptor agonist, molecular mechanisms, gut microbiota, multi-organ protection, therapeutic repurposing Citation Gong B, Li C, Shi Z, Wang F, Dai R, Chen G and Su H (2025) GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy