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doi: 10.3389/fcvm.2024.1446468 30 ManuboluVSLakshmananSKinningerAAhmadKSusarlaSSeokHJet al

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Of the signalling molecular mechanisms related to high inflammation, NF-kB, NLRP3, TGF-, TLR4, cleaved caspase 3 and phosphorylated JNK showed significant increases in the forest plots, which also reflect the establishment of DCM in this rodent model and the need for an anti-inflammatory approach to attenuate DCM in the preclinical subjects