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1 A total of 18,582 matched patients, 9291 in each group, were analyzed

This may be more common in patients who: are under-eating recently lost significant weight have poor protein intake are combining multiple wellness therapies simultaneously Injection Site Reactions Because many peptide therapies are injectable, patients may occasionally notice: redness swelling itching bruising tenderness Injection technique and sterile handling matter significantly

Common side effects include: Nausea Diarrhea Vomiting Constipation Stomach pain Reduced appetite Headache Serious Side Effects (Uncommon) Pancreatitis (pancreatic inflammation) Gallbladder issues Kidney damage, often due to dehydration from nausea or vomiting Serious allergic reactions Vision changes in type 2 diabetes patients Increased heart rate A boxed warning alerts users to the potential risk of thyroid C-cell tumors, as observed in animal studies

Key Takeaway: If the dosage is high enough, the pill is just as effective as the injection for weight loss

Hypoglycemia is rare with monotherapy but can occur if combined with insulin or sulfonylureas