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In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]

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Realdon, S

At age 20, plasma levels average approximately 200 ng/mL

46,47,48 Overall, these outcome parameters might be too rough to capture potential adverse pulmonary effects of paracetamol, and more subtle outcomes, such as need for home oxygen or respiratory medication might be more informative