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In clinical trials, participants typically started to notice significant weight loss within the first 12 to 16 weeks of treatment

Lean mass decreases too

Acetyl-L-carnitine, a key hub molecule linking lipid metabolism and energy metabolism, also exhibits significant changes in children with DRE (142)

GABA has three receptors, i.e., GABAA, GABAB, and GABAC, on the post-synaptic neurons (Briggs and Galanopoulou, 2011), and among them, GABAA is of critical importance as this receptor is involved in controlling and balancing action potential and main target of the AEDs