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Potential indirect mechanisms that could theoretically influence libido include: Nutritional deficiencies if caloric restriction is excessive Fatigue or low energy during the initial treatment phase Hormonal fluctuations associated with adipose tissue loss Psychological adjustment to body image changes Patients should be reassured that sexual side effects are not a recognised feature of Wegovy therapy, but any persistent concerns warrant clinical evaluation to exclude other contributing factors

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Updated report on tools to measure outcomes of clinical trials in fragile X syndrome