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It often builds slowly, and the cosmetic signs tend to show up alongside subtler systemic symptoms that are easy to dismiss
Bjerre KL, Madsen LW, Andersen S, et al
in: Journal of Molecular Biology , 267 (1997)4, 1039-1052) Previous studies of model peptides have also shown that salt bridges spaced at i,i +4 along the peptide chain are more stabilizing than those spaced at i,i +3, with a preference for the order acid-base rather than base-acid from the N- to the C- terminus
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In our study, we show that GLP-1-RAs are superior to UCWM both with respect to the extent of weight loss and the proportion of patients achieving the recommended 10% weight loss, highlighting the potential of concomitant pharmacological treatment for weight management in IIH
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