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Moreover, most of the existing preclinical studies have relied on male rodents, neglecting sex-specific variants in gut microbiota compositions and neuroinflammatory responses (Chakraborty et al., 2025)

Finally, given the robust adipose remodeling observed here, it will be essential to evaluate whether similar molecular and metabolic adaptations occur in human adipose depots, which differ from rodents in distribution and responsiveness

Eisermann K, Fraizer G

84 Published in 2014, the HELP study (Hepatic Encephalopathy: Lactulose vs

For Aging and Longevity: As we age, glutathione levels naturally decline, contributing to increased oxidative stress and cellular damage