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Lipohypertrophy is primarily associated with repeated mechanical trauma to the same tissue area

The unknowns far outweigh the unproven benefits

The pH of the topical formulation also affects GHK-Cu dosage outcomes

Future research should prioritize elucidating the molecular mechanisms behind the antitumor effects, refining individualized treatment strategies, investigating early tumor prevention applications, assessing potential benefits for non-diabetic populations, advancing the development of novel therapies, establishing robust safety monitoring frameworks, and building precision medicine decision-making platforms

International Journal of Molecular Sciences, 25(17), 9351