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Improved wound healing, reduced inflammation, reduced hepatic fat content, decreased infarct size following myocardial infarction or intracranial stroke, improved vascular function with decreased oxidative stress, improved endothelial dysfunction, and lowering of albuminuria have also been observed in pre-clinical studies [24]

If the skin lacks the elasticity to contract over a newly reduced area, the result can appear hollow or sagged rather than contoured

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