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The ALAD protein, which is a known target for TRXs and NTRC, was used as a positive control ( Figures 5B, C )

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siRNA targeting LRP5 (GGACAGACUCAGAGAGACCAA) was transferred into the BMSCs with the help of Lipofectamine 3000 (Invitrogen, United States), and all operations were carried out under the manufacturers instructions

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