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To induce intracellular GSH depletion, cells were incubated in Cys 2 -free medium or with BSO (1000 M) treatment or erastin (10 M) treatment
Brown MA, Stevenson EJ, Howatson G
Even less is known regarding its potential role in tumour metastasis and the potential side effects of GSH catabolism in specific tissues (for example, release of glutamate in brain metastasis)
if you take them out, the IRR goes down
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