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What is more, no clear trend for a change in pharmacokinetics was evident across groups with increasing renal dysfunction 12 that allowed us to administer the same dose of the drug and the same blood sampling time points in patients with different degree of renal impairment who were included in our study

This has led many people to look toward supplementation to bridge the gap and support their natural resilience

However, additional analyses without imputation showed that the findings are consistent with those based on the analyses with imputation