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Why Titration Matters More for Retatrutide Than Other GLP-1s In the Phase 2 trial, GI adverse events (primarily nausea, vomiting, and diarrhea) affected 50 to 60 percent of participants at higher doses, according to Jastreboff et al

Cumulative incidence was estimated with the Kaplan-Meier method and the log-rank test was performed to compare the difference

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