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GLP-1RA also increased AMPK activity in microglia, suppressing neuroinflammation and promoting phagocytosis of -amyloid peptides [49]

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Particular caution is warranted with insulin (hypoglycemia risk), sulfonylureas (hypoglycemia risk), blood thinners like warfarin (altered absorption), and oral contraceptives (potentially reduced efficacy)

The preclinical data are interesting enough to warrant proper human investigation, but it is not sufficient to justify self-experimentation