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Participants endorsing Semaglutide and Tirzepatide use reported fewer drinks as measured by the TLFB, fewer binge episodes, and lower AUDIT scores compared to controls and compared to before starting their medication

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The two peptides have separate FDA concerns: FDA flagged CJC-1295 for limited clinical data and serious adverse events including increased heart rate and systemic vasodilatory reaction

European journal of clinical nutrition , 72 (1), 105111

The study highlights the potential mediating role of these factors in the treatment effect of semaglutide on HRQoL