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Nausea (most common, typically dose-dependent and transient) Diarrhea or constipation during dose escalation Vomiting, especially when starting or increasing dose Reduced appetite and early satiety Injection site reactions (redness, bruising) Fatigue, particularly in early weeks Rare: Pancreatitis discontinue immediately with severe abdominal pain Rare: Thyroid C-cell effects (contraindicated with MEN2 or thyroid cancer history) AOD-9604 is a modified C-terminal fragment (residues 176191, Tyr-hGH177-191) of human growth hormone, studied for lipolytic and anti-obesity properties

DJH and BRR receive financial support from the Australian Research Council Linkage Projects scheme (LP140100095)

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Recent evidence suggests that cellular senescence plays a role in promoting fibrosis, especially in aged tissues, where stress-induced senescent myofibroblasts may exhibit delayed clearance with age

Antioxidant Protection: Protects cells from oxidative stress and free radical damage