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This vitamin b12 deficiency skin problems tend to cause darkening of the skin, patchy, especially on the hands, feet, and joints

Across these end-points the reported pattern is consistent: aged animals treated with the peptide trend toward biomarker profiles characteristic of younger animals, although effect sizes are typically modest and methods of measurement vary across publications

Ithaca: Cornell University Press

Dose reduction typically resolves these effects within a few days

While its best-known role is in erythropoiesis (red blood cell formation), its also involved in: DNA synthesis Regeneration of bone marrow, GI lining, and respiratory tract lining Nervous system development and maintenance (11) Prevention of anemia Although a B12 deficiency isnt as common as vitamin D or even folate, it still happens