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Its a direct consequence of the peptide doing its job
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Age-related changes in renal function, hepatic metabolism, and tissue perfusion theoretically could influence peptide clearance and distribution, though no studies have systematically examined age effects
No overall differences in safety or efficacy were detected between these patients and younger patients, but greater sensitivity of some older individuals cannot be ruled out
Resveratrol and SRT-1720 directly activate SIRT1 or indirectly through the activation of AMP-activated protein kinase (AMPK) which is the cofactor for SIRT1 activity (Liang et al
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