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Clinical trials showed joint pain occurred at similar rates in tirzepatide and placebo groups, and joint inflammation is not a known pharmacologic effect of GIP or GLP-1 receptor activation
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This dual-action mechanism supports more significant weight loss compared to other treatments, making it an excellent option for those struggling to manage their weight
Lixisenatide, another short-acting GLP-1RA, did not provide evidence of CV RR in the ELIXA (The Evaluation of Lixisenatide in Acute Coronary Syndrome) trial (4)
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