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ACTIN-forward: 5-CATGTACGTTGCTATCCAGGC-3

Once reconstituted, both compounds require refrigeration and have finite use windows before potency declines

STEP-HFpEF trial found substantial improvement of HF symptoms in patients with HFpeEF and obesity

Sermorelin in this population will amplify existing pulses, but the degree of additional IGF-1 and body composition effect is not established