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Also, glutamate excitotoxicity NMDA-mediated intra-neuronal calcium overload elevates NO synthesis contributing to oxidative stress particularly the production of reactive nitrogen species which are able to cause defects in DNA and protein phosphorylation pathway (85)

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Its long-acting profile has generated significant scientific interest in studies involving body composition and weight-management mechanisms

Effects of GH Signaling on Therapy Resistance in Cancer Radiotherapy In vitro studies, researchers have clearly shown that GH treatment conferred radio-resistance in tumor cells