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CntA oxygenase substrate profile comparison and oxygen dependency of TMA production in Providencia rettgeri
10.1038/nature09922 81 WangZ.RobertsA
Notably, eosinophils of asthmatic patients exhibit lower GLP-1Rs expression compared to healthy controls (46)
For patient education, half-life plotters can visually explain why missing a single dose has limited impact on overall drug levels at steady state, but also why consistent weekly dosing is important for maintaining effective concentrations
Finally, the increasing off-label use of GLP-1 RAs for weight loss in non-diabetic individuals may further exacerbate access limitations and drug shortages, potentially disadvantaging patients with T2DM
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