glutathione and mthfr mutation Converging Evolutionary, Environmental Clinical Ideas on Folate Metabolism Katie Wiekamp | Comment DETOX

Oxidative Stress and Neuroprotection Sviridov, I

10.1016/j.chemphyslip.2022.105252 99 GeorgievaR.MomchilovaA.PetkovaD.KoumanovK.StanevaG

Improved cognitive function: Vitamin B12 is also important for cognitive function

A decrease in the fatty acid metabolite heptanoic acid was also observed, indicating an increased use of fatty acids as an alternative energy source, via -oxidation to acetyl-CoA and propionyl-CoA 85 .This use of fatty acids is further reinforced by elevated malonate levels in barren urchins, as malonate is converted to malonyl-CoA via the ATP-dependent enzyme acetyl-CoA carboxylase, the primary step in fatty acid synthesis 91

Here is what the clinical data actually shows when you line up the results side by side