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Studies have shown that DSIP can pass the blood brain barrier (BBB) in rats, mice, dogs, and humans, making it a potential option for targeting neurological disorders, aforementioned mood disorders, and sleep disorders [11]

The Research Gap Phase I safety trials have been conducted but results were never published despite completed status

2005;288:F5528

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However, TRIM28 peaks only partially and inconsistently overlapped with regions of increased ATAC-seq signal or AP2 binding sites, suggesting that additional mechanisms beyond the currently proposed TRIM37TRIM28AP2 model may contribute to the regulation of somatic gene repression in PGCs