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It works by making the pancreas produce more insulin (a hormone that helps your body use the energy from food) and by reducing the amount of glucagon (a hormone that raises the levels of sugar in your blood) in the body
Its advisable to start with a lower dose and gradually increase it to minimize these effects
HCT116 cells are an extensively used human colorectal model that carry a KRAS G13D mutation but retain wild-type TP53 and APC 17
However, if you experience spreading warmth, pus drainage, fever, or increasing swelling 24-48 hours after injection, contact your healthcare provider immediately as these may indicate infection
doi: 10.1007/s11306-018-1448-3 24 HaJHJayaramanMNadhanRKashyapSMukherjeePIsidoroCet al
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