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While results vary from person to person, the following areas are where this duo is most commonly applied
10.3389/fimmu.2022.932152 93 SiesH.JonesD
Dosing Comparison# Retatrutide Dosing# Based on Phase 2 clinical trial protocols (investigational only): Starting dose : 0.5 mg weekly subcutaneous injection Escalation : Gradual increase over 12-24 weeks to target dose (up to 12 mg) Target doses tested : 1, 4, 8, and 12 mg weekly Escalation rationale : Extended 24-week escalation for higher doses reduces GI side effects compared to faster 12-week escalation No commercial formulation exists
This strategy mirrors the approach used with GLP-1 maintenance dosing , where starting low and titrating up reduces side effects across the board
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