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In the ED: Fasting history is unreliable Treat as higher aspiration risk especially if symptomatic Anticipate vomiting and difficult visualization Practical considerations: Optimize positioning (ramped, head elevated, or slight reverse Trendelenburg) Use RSI when appropriate Minimize bag-mask ventilation Ensure suction is immediately available and functioning
Never discontinue Mounjaro without medical guidance
Both medications carry important safety warnings: Adderall has a boxed warning regarding abuse and dependence potential, while semaglutide products carry a boxed warning about thyroid C-cell tumor risk
GLP-1 RAs are increasingly used in the treatment of T2DM due to their multifaceted benefits, including improving glycemic control, reducing body weight, enhancing -cell function, and yielding favorable cardiovascular and renal outcomes [22]
Tirzepatide activates both GLP-1 and GIP pathways, while semaglutide primarily activates the GLP-1 pathway
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