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In patients with cirrhosis of alcoholic or MASH etiology, intrahepatic MAIT cells are reduced in abundance and are found mainly within fibrotic septa, in close proximity to myofibroblasts
G6PD deficiency typically manifests as haemolytic anaemia due to red cell oxidative damage but, in severe cases, also results in infections due to lack of leucocyte oxidative burst, highlighting the dual redox roles of the pathway in free radical production and detoxification
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