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The study included a 26-week treatment period including up to six weeks of dose escalation, followed by a 6-week post-treatment follow-up, extending to week 32
The interaction very rarely results in a pernicious anemia that appears reversible with discontinuation of metformin or with Methylcobalamin, vitamin B12 supplementation
Still, anyone with significant heart disease, uncontrolled hypertension, or history of cardiac events should consult their cardiologist before using any research compound
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