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Tachycardia Most patients see at least some heart rate increase on GLP-1 drugs, but some studies have shown significant jumps into the range of tachycardia

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These include the HMOX1 (heme oxygenase 1), NQO1 [NAD(P)H quinone oxidoreductase 1], GCLC (glutamate-cysteine ligase catalytic subunit), GCLM (glutamate-cysteine ligase modifier subunit), PRDX1 (peroxiredoxin 1), and TXNRD1 (thioredoxin reductase 1) genes

Data from 2005 Q2 to 2024 Q3 suggested NAEs persisted as a substantial AE subset associated with GLP-1 RAs based on FAERS

Diabetologia 63 , 13961407 (2020)