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Yamato et al
However, the concurrent use of CYP-inducing medications may decrease the half-life to ~9 hours
Feb 2021;44(2):433-439
The targeted application and localized action minimize this risk
Melatonin reduces disseminate neuronal death after mild focal ischemia in mice via inhibition of caspase-3 and is suitable as an add-on treatment to tissue-plasminogen activator
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